{"id":24,"date":"2025-11-01T13:57:02","date_gmt":"2025-11-01T13:57:02","guid":{"rendered":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/?post_type=product&#038;p=24"},"modified":"2025-11-07T09:59:28","modified_gmt":"2025-11-07T09:59:28","slug":"alli","status":"publish","type":"product","link":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/product\/alli\/","title":{"rendered":"Alli"},"content":{"rendered":"<h1>Medication Overview: Alli<\/h1>\n<h2>Generic Name<\/h2>\n<p>\n<a href=\"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/product\/xenical\/\" data-internallinksmanager029f6b8e52c=\"28\" title=\"Xenical\">Orlistat<\/a>.\n<\/p>\n<h2>Drug Classification<\/h2>\n<p>\nLipase inhibitor.\n<\/p>\n<h2>Mechanism of Action<\/h2>\n<p>\nAlli inhibits gastrointestinal lipases, reducing the absorption of dietary fats by approximately 25%. It acts locally within the gastrointestinal tract to block the breakdown and absorption of about one-third of the fat consumed in a meal. Unabsorbed fat is then excreted in the stool.\n<\/p>\n<h2>Indications for Use<\/h2>\n<p>\nAlli is indicated for overweight adults with a Body Mass Index (BMI) of 25 or greater. It is recommended as an adjunct to a reduced-calorie, low-fat diet and increased physical activity for weight management.\n<\/p>\n<h2>Dosage and Administration<\/h2>\n<p>\nThe recommended dose of Alli is one 60 mg capsule taken with each main meal containing fat. It should be taken during or up to one hour after the meal. If a meal is missed or contains no fat, the dose of Alli can be skipped. Avoid exceeding the dosing frequency of three times per day.\n<\/p>\n<h2>Contraindications<\/h2>\n<p>\nAlli is contraindicated in patients with chronic malabsorption syndrome or cholestasis. It should not be used in individuals with known hypersensitivity to Orlistat or any component of the product.\n<\/p>\n<h2>Possible Drug Interactions<\/h2>\n<p>\nCo-administration with cyclosporine significantly reduces cyclosporine plasma levels. Alli may also affect the absorption of fat-soluble vitamins (A, D, E, K) and beta carotene. Patients on oral contraceptives may experience reduced effectiveness if gastrointestinal effects occur.\n<\/p>\n<h2>Storage Conditions<\/h2>\n<p>\nStore Alli at controlled room temperature, between 20\u00b0C to 25\u00b0C (68\u00b0F to 77\u00b0F). Protect from moisture and keep the bottle tightly closed. The desiccant in the bottle should remain in place for optimal product stability.\n<\/p>\n<h2>Special Populations<\/h2>\n<h3>Pregnancy and Lactation<\/h3>\n<p>\nThe use of Alli is not recommended during pregnancy. There is no sufficient data on the use of Orlistat in pregnant or breastfeeding women. Breastfeeding mothers should avoid using this medication due to the potential risk of affecting the infant&#8217;s nutritional intake.\n<\/p>\n<h2>Pediatric Use<\/h2>\n<p>\nThe safety and efficacy of Alli in pediatric patients below the age of 18 have not been established. It should not be administered to children due to the lack of clinical data supporting its use in this population.\n<\/p>\n<h2>Elderly Use<\/h2>\n<p>\nClinical studies of Alli did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Caution should be exercised when prescribing to elderly patients, especially those with underlying health conditions.\n<\/p>\n<h2>Renal Impairment<\/h2>\n<p>\nThere are no specific dosage adjustments provided in the product labeling for patients with renal impairment. However, patients with severe renal insufficiency should consult a healthcare provider before starting Alli due to potential risk factors.\n<\/p>\n<h2>Hepatic Impairment<\/h2>\n<p>\nAlli has not been studied in patients with hepatic impairment. No specific dosage adjustments are provided, but caution is advised when using the medication in this population.\n<\/p>\n<h2>Adverse Reactions<\/h2>\n<h3>Gastrointestinal Effects<\/h3>\n<p>\nCommon adverse reactions include oily spotting, flatulence with discharge, fecal urgency, fatty\/oily stool, and increased defecation. These symptoms generally decrease with continued use and adherence to a low-fat diet.\n<\/p>\n<h3>Hepatic Events<\/h3>\n<p>\nRare cases of severe liver injury have been reported in post-marketing surveillance. Symptoms include jaundice, dark urine, pruritus, and upper right quadrant pain. These warrant immediate medical attention.\n<\/p>\n<h3>Dermatological Reactions<\/h3>\n<p>\nRare instances of hypersensitivity reactions, including anaphylaxis and angioedema, have been reported. Patients should be monitored for signs of severe skin reactions, rash, or itching.\n<\/p>\n<h2>Patient Counseling Information<\/h2>\n<p>\nPatients should be advised to adhere to a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat. They should distribute daily intake of fat, carbohydrates, and protein over three main meals. Encourage patients to take a multivitamin supplement once daily, at least two hours before or after taking Alli.\n<\/p>\n<h2>Use with Diabetes<\/h2>\n<p>\nPatients with <a href=\"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/product\/glucophage\/\" data-internallinksmanager029f6b8e52c=\"35\" title=\"Glucophage\">type 2 diabetes<\/a> receiving treatment with medications such as metformin or insulin should consult their healthcare provider before starting Alli. <a href=\"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/product\/ozempic\/\" data-internallinksmanager029f6b8e52c=\"37\" title=\"Ozempic\">Weight loss<\/a> can improve glycemic control, potentially necessitating adjustments in antidiabetic medication dosages.\n<\/p>\n<h2>Monitoring Parameters<\/h2>\n<p>\nRoutine monitoring may include checking liver function tests, renal function, and assessing vitamin levels, especially fat-soluble vitamins. Attention should be paid to any new or worsening symptoms of gastrointestinal discomfort or hepatic dysfunction.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alli is a medication used to help people lose weight. The active ingredient in Alli is orlistat. It is also known by its brand name, Xenical. Alli works by blocking some of the fat from being absorbed in your diet.<\/p>\n<h2>Alli Price<\/h2>\n<p>Typically, Alli is priced from \u00a30.72 up to \u00a31.09 per pills. Variance in price is rooted in the pack&#8217;s volume and the concentration of active entities (30 or 360 mg).<\/p>\n","protected":false},"featured_media":54,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[17],"product_tag":[],"class_list":{"0":"post-24","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-weight-loss","7":"pa_active-ingredient-orlistat","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-external"},"_links":{"self":[{"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product\/24","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/comments?post=24"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/media\/54"}],"wp:attachment":[{"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/media?parent=24"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product_brand?post=24"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product_cat?post=24"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product_tag?post=24"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}