{"id":260,"date":"2025-11-05T20:40:27","date_gmt":"2025-11-05T20:40:27","guid":{"rendered":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/?post_type=product&p=260"},"modified":"2025-11-07T09:59:24","modified_gmt":"2025-11-07T09:59:24","slug":"allegra","status":"publish","type":"product","link":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/product\/allegra\/","title":{"rendered":"Allegra"},"content":{"rendered":"

Medication Name: Allegra<\/h1>\n

Active Ingredient<\/h2>\n

Fexofenadine hydrochloride is the active ingredient in Allegra. It is a second-generation antihistamine<\/a> and a selective peripheral H1-blocker. Fexofenadine is a non-sedating antihistamine that works by reducing the effects of histamine in the body.<\/p>\n

Indications and Usage<\/h2>\n

Allegra is indicated for the relief of symptoms associated with seasonal allergic rhinitis<\/a> in adults and children 12 years and older. It alleviates sneezing, rhinorrhea, pruritus, and lacrimation. This medication is also indicated for the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria.<\/p>\n

Dosage Forms<\/h2>\n

Allegra is available in several dosage forms. These include oral tablets (30 mg, 60 mg, and 180 mg), orally disintegrating tablets (30 mg), and oral suspension (30 mg\/5 mL). These varied forms facilitate tailored dosing for different patient needs and preferences.<\/p>\n

Dosage and Administration<\/h2>\n

Adults and children 12 years and older with seasonal allergic rhinitis are recommended to take 60 mg twice daily or 180 mg once daily with water. For chronic idiopathic urticaria, the dosage is the same. No adjustment is necessary in patients 12 years and older with decreased renal function. The oral suspension should be shaken well before use and measured with a dosing spoon or oral syringe.<\/p>\n

Pharmacokinetics<\/h2>\n

Fexofenadine has rapid absorption with a peak plasma concentration reached in approximately 1-3 hours. It is 60-70% protein-bound in serum. Fexofenadine is not significantly metabolized by the liver and undergoes limited metabolism, with approximately 11% of the dose excreted unchanged in the urine. The terminal elimination half-life is 14.4 hours after multiple dosing in healthy subjects.<\/p>\n

Drug Interactions<\/h2>\n

Significant drug interactions with fexofenadine include antacids containing aluminum or magnesium, which should not be taken within 15 minutes of Allegra. Co-administration with ketoconazole or erythromycin<\/a> increases fexofenadine plasma levels. Concomitant use with fruit juices, particularly grapefruit, orange, and apple, may decrease the bioavailability of fexofenadine.<\/p>\n

Contraindications<\/h2>\n

Allegra is contraindicated in patients with known hypersensitivity to fexofenadine or any of its ingredients. It is also contraindicated in patients with severe renal impairment due to potential accumulation of the drug in the body.<\/p>\n

Mechanism of Action<\/h2>\n

Fexofenadine works by selectively inhibiting peripheral H1 receptors. By blocking H1 receptors, it prevents the action of endogenous histamine, which results in diminished allergic symptoms such as nasal congestion, vasodilation, and increased vascular permeability.<\/p>\n

Special Populations<\/h2>\n

Pharmacokinetic data suggest no substantial differences in efficacy or safety in elderly patients compared to younger adults. Caution is recommended in patients with renal impairment, and adjustment may be necessary. Limited observational data in pregnant women have shown no increase in major malformations, but it should be used during pregnancy only if clearly needed.<\/p>\n

Clinical Studies<\/h2>\n

Allegra has been evaluated in multiple placebo-controlled clinical trials. Studies have shown significant improvement in allergic rhinitis symptoms compared to placebo. In chronic idiopathic urticaria, Allegra significantly reduced itching and wheal size. These trials provide strong evidence of Allegra’s efficacy and safety in treating both conditions.<\/p>\n

Adverse Reactions<\/h2>\n

The most common adverse reactions observed include headache, drowsiness, dizziness, and nausea. Other less frequent side effects include fatigue, dyspepsia, and back pain. Most adverse reactions are mild to moderate in severity and typically resolve without intervention.<\/p>\n

Storage and Handling<\/h2>\n

Allegra should be stored at controlled room temperature, between 20\u00b0C to 25\u00b0C (68\u00b0F to 77\u00b0F). The oral suspension should be discarded after 30 days of opening. Keep out of reach of children to prevent accidental ingestion, and ensure the container is tightly closed after each use.<\/p>\n

Overdosage<\/h2>\n

Overdose is generally characterized by dizziness, dry mouth, and fatigue. In case of overdose, supportive treatment is recommended. Hemodialysis does not remove a significant amount of fexofenadine from the blood. Immediate medical attention is advisable for cases of severe overdose.<\/p>\n

Patient Counseling<\/h2>\n

Instruct patients to take Allegra with water and advise against consuming fruit juices concurrently. Patients should be informed about the potential for drowsiness and should avoid engaging in activities requiring mental alertness until they know how the medication affects them. Emphasize adherence to recommended dosage schedules for optimal therapeutic outcomes.<\/p>\n","protected":false},"excerpt":{"rendered":"

Allegra, also known as fexofenadine, is an over-the-counter medication used to treat allergy symptoms like sneezing, runny nose, and itchy eyes. The active ingredient in Allegra, fexofenadine, helps to reduce the effects of natural histamines in the body, providing relief from seasonal allergies.<\/p>\n

Allegra Price<\/h2>\n

The general market rate for Allegra varies from \u00a30.22 to \u00a30.64 per pills. Determining factors include the size of the packaging and the potency of its components (60 or 360 mg).<\/p>\n","protected":false},"featured_media":290,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[290],"product_tag":[],"class_list":{"0":"post-260","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-allergies","7":"pa_active-ingredient-fexofenadine","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-external"},"_links":{"self":[{"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product\/260","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/comments?post=260"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/media\/290"}],"wp:attachment":[{"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/media?parent=260"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product_brand?post=260"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product_cat?post=260"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/bannviewmedicalpractice.co.uk\/pharmacy\/wp-json\/wp\/v2\/product_tag?post=260"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}